WHEN SCIENCE MEETS FARMING, GREAT THINGS HAPPEN

Slide Three

COSEICURETM

rumen available:

ionic cobalt

selenium

iodine

ionic copper

available for cattle and sheep

Slide One

Think this cow has copper deficiency?

Think again!

Slide Three - copy

COSECURETM

rumen available:

ionic cobalt

selenium

ionic copper

available for cattle, sheep and lambs

Slide Two

Dissolution of a
COSECURETM bolus

Our boluses dissolve very slowly over a course of months, at a controlled and constant rate.

Slide Three

ZINCOISELTM

rumen available:

ionic zinc

selenium

iodine

ionic cobalt

available for sheep

Slide
THINKING ABOUT
FERTILITY?
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Super User

Super User

Thursday, 03 July 2014 19:43

Testimonial 4

James Martin is a an award winning farmer from Northern Ireland, who was named winner at this year’s prestigious Balmoral event. He uses the COSEICURE Cattle boluses annually on his herd and has been extremely happy with the results.

James commented; ‘ I use CoseIcure Cattle Boluses every year without fail on my premier Belgium Blues and have had great results. I had used other boluses in the past but they did not live up to my expectations. The CoseIcure boluses have not only addressed mineral deficiencies in the herd, but I have also seen a marked improvement in weight gain, thrive and herd fertility. I find them extremely convenient to use, as a single application provides a steady supply of cobalt, selenium iodine and copper over the entire grazing season. Increased weight gain gives me a competitive edge; allowing me to secure top market prices and the improved condition and healthy coat which results from their use, was instrumental in my win at this year’s balmoral event.

James Martin Newtownards, Co Down
Tuesday, 27 May 2014 17:24

Testimonial 3

The COSECURE and Zincosel cattle and sheep boluses perform very well on my clients’ farms.

In the cattle this has become very mainly at calving time. I have observed that cattle which use the Cosecure range often calve down faster. The resulting calf is up and sucking very quickly. The dam then cleanses within 24 hours and there is a reduced incidence of endometritis at 21 days post calving.

In the sheep the lambs which have benefitted from the product have a better live weight gain, meaning they are sold earlier. The ewes have a better pregnancy rate compared to those which have not had the product.

I also very much appreciate the technical support we get from the company. They display a very responsible attitude to the recommendation of boluses on farms and do not recommend the products unless a need for supplementation has been shown. This truly independent advice is very rare in a large company.

Oli Hodgkinson BVSc, Cert. SH&P, MRCVS, partner at Trefaldwyn Vets in Montgomery, Powys, UK.
Wednesday, 26 March 2014 12:48

Testimonial 2

I have been using COSECURE boluses on my hill ewes for the last 7 years and I am very happy with the results, especially as my hill ewes receive no supplementary feeding.

Iain MacKay, Torloisk Farm
Thursday, 07 April 2016 15:40

Testimonial 14

The CoseIcure soluble glass boluses supply the same levels of ionic copper, cobalt, selenium and iodine every single day for up to 6 months. These trace elements can play a vital role in fertility and health.

The CoseIcure range is enjoying rapid growth in Ireland; and is being increasingly specified by farmers, vets and merchants, who are looking for a high quality bolus that provides a solid return on investment.

One such farmer is Aiden Leddy click here to learn about the difference that CoseIcure cattle boluses have made on his farm.

Monday, 13 August 2018 13:16

Research & Trial Work

Scientific Papers

click on a link to view a report or trial.

Effects of a Long Acting Trace Mineral Rumen Bolus Upon Range Cow Productivity
Jim E. Sprinkle2, David W. Schafer2, Paul Cunco2, Doug Tolleson2 and R. Mark Enns32The University of Arizona, Tucson, Arizona, 3Colorado State University, Fort Collins, Colorado

Effects of three types of trace element supplementation on the fertility of three commercial dairy herds
D.H. Black, N.P. French, The Veterinary Record, May 22, 2004

The Effect of Cosecure on the conception rate and trace element status of dairy cattle
A.M. Mackenzie, M.M. Moeini and S.B. Telfer, Department of Animal Physiology and Nutrition, University of Leeds

Effect of a Soluble Colbalt, Selenium and Zinc Glass Bolus on Humoral Immune Response and Trace Elements Status in Lambs
N.R. Kendall, A.M. Mackenzie, and S.B. Telfer, Department of Animal Physiology and Nutrition, University of Leeds

Measuring copper status
Telsol

The molecular basis of copper and iron interactions
Paul Sharp, Centre for Nutrition and Food Safety, School of Biomedical and Molecular Sciences, University of Surrey

Role of rumen in copper and thiomolybdate absorption
L. Gould and N.R. Kendall, School of Veterinary Medicine and Science, University of Nottingham

The Responses to Increased Trace Element Inclusion
S.B. Telfer, Department of Animal Physiology and Nutrition, University of Leeds

The effect of a zinc, cobalt and selenium soluble glass bolus on trace element status of extensively grazed sheep over winter 
N.R. Kendall1, D.W. Jackson1, A.M. Mackenzie2, D.V. Illingworth1, I.M. Gill3 and S.B. Telfer1
1Centre for Animal Sciences, Leeds Institute of Biotechnology and Agriculture, School of Biology, University of Leeds, 2School of Agriculture, Harper Adams University College, 3Thrums Veterinary Group

Effect of a copper, cobalt and selenium glass bolus given to grazing sheep 
N.R. Kendall1, A.M. Mackenzie2, S.B. Telfer3
1School of Human Development, Academic Division of Reproductive Medicine, Queen's Medical Centre, 2Harper Adams Animal Science Research Centre, Harper Adams University College, 3Centre for Animal Sciences, Leeds Institute of Biotechnology and Agriculture, School of Biology, University of Leeds

The Effect of a Zinc, Cobalt and Selenium Soluble Glass Bolus on Trace Element Status and Semen Quality of Ram Lambs  
N.R. Kendall, S. McMullen, A. Green, R.G. Rodway, Centre for Animal Sciences, Leeds Institute of Biotechnology and Agriculture, School of Biology, University of Leeds

The Effect of Soluble-glass Boluses Containing Copper, Cobalt and Selenium on the Blood Composition of Ewes 
G. Zervas1, S.B. Telfer2, G. Carlos3
1Agricultural College of Athens, Greece, 2Department of Animal Physiology and Nutrition, University of Leeds, 3Central Veterinary Laboratory, New Haw, Weybridge, Surrey

How To's

click on a link to view one of the instructions.

Cattle Bolus Applicator Instructions
Sheep Bolus Applicator Instructions
Lamb Bolus Applicator Instructions

Monday, 13 August 2018 13:03

Copper Myths - Sidebar

Think you know about copper? Think you know about boluses? Did you know that some commonly held beliefs about copper, copper deficiency and nutritional supplements are not correct.

Click on the copper myths below to find out the facts.

Monday, 13 August 2018 13:00

Myths Copper

Cosecure boluses contain a unique form of rumen-available ionic copper.
Let’s find out a bit more about why this is significant.

 

Is All Copper The Same And Are All Boluses The Same?

The critical difference between Cosecure and other nutritional supplements is that Cosecure supplies rumen-available elements.

The copper in our unique boluses is in the form of ionic copper, which is active in the same pH range as the rumen. This means that the minerals are highly available to the animals in the rumen.

Some boluses supply copper in the form of Copper Oxide. Copper Oxide is active at much lower pH levels, and requires exposure to abomasal acidity before release of the copper.

Why does it matter if the elements are rumen available?

The cow will ingest molybdenum and sulphur through its diet. Molybdenum and sulphur bind together to form something called Thiomolybdate. Thiomolybdate is very ‘copper-hungry’. It binds with copper in the rumen and when there is no copper left in the rumen, it moves into the bloodstream and binds to the copper-co-dependent enzymes there.

These enzymes are vital for fertility and productivity. When the molybdenum and sulphur combination (thiomolybdate) binds with these copper enzymes in the blood, they are rendered inactive, so fertility and productivity are impaired. Some farmers will know this as ‘copper lock’ or ‘secondary copper deficiency’. We know it as TMT (or thiomolybdate toxicity).

To stop ‘copper lock’ or ‘TMT’ occurring, we need to stop the molybdenum and sulphur combination (thiomolybdate), from moving out of the rumen and into the bloodstream. The only way to do this is to supply enough copper in the rumen to satisfy the thiomolybdate’s ‘copper hunger’.

Because Cosecure’s copper is rumen-available, it is able to do this. It supplies copper in the rumen continuously for up to 6 months, meaning the thiomolybdate doesn’t pass into the blood in search of more copper; it doesn’t bind with the blood’s copper-dependent enzymes and it therefore doesn’t impair fertility and productivity.

The boluses also contain rumen-available ionic cobalt. Why is it important that the boluses also supply rumen-available cobalt?

Unlike cobalt-oxide boluses, the Cosecure boluses supply ionic cobalt which is rumen-available.

Bacteria in the rumen require cobalt in order to synthesize Vitamin B12. Vitamin B12 is vital for energy utilisation and productivity. The body has no capacity to store cobalt, so Cosecure’s ability to continually supply rumen-available cobalt for up to 6 months is ideal for improving cobalt supply and promoting health in cattle.

What other factors affect that fertility, immunity, thrive and productivity?

Lots of factors! Fertility, immunity, thrive and productivity are extremely complex issues with many causes and it is important to always consult a vet and understand your herd’s nutritional status before using any boluses, medicines or other nutritional products. For more information on the bolus range, contact your vet.

Monday, 13 August 2018 12:54

COSEICURE Cattle

Direct-to-Rumen, Continuous Release Nutritional Bolus pdfDownload the Data Sheet

USES

For the supply of copper, cobalt, selenium and iodine in cattle. The bolus supplies these trace elements at a controlled and constant rate for up to 6 months.

Each Bolus Contains:

  • 13.4% w/w ionic copper
  • 0.50% w/w ionic cobalt
  • 1.00% w/w iodine
  • 0.15% w/w selenium

Presentation

Continuous release intraruminal device. A cylindrical, blue glass continual release intraruminal device approximately 82mm x 24mm and weighing approximately 100g.

*COSEICURE boluses are not a registered medicine, such as require authorisation by the HPRA

Are they different from other boluses?

Yes. Bimeda revolutionary boluses are completely unique

stomachThrough releasing ionic copper in the rumen, Cosiecure is the only true dissolving bolus, and dissolves at a slow but constant rate.

Cattle Bolus Applicator Instructions

Cattle Applicator Instructions

Download Applicator Instructions

Monday, 13 August 2018 12:53

COSECURE Cattle

Direct-to-Rumen, Continuous Release Nutritional Bolus pdfDownload the Data Sheet

INDICATIONS

Supplies ionic copper, ionic cobalt and selenium at levels compatible with the animal’s daily requirements for up to six months.

Each Bolus Contains:

  • 13.4% ionic copper
  • 0.50% ionic cobalt
  • 0.30% selenium as sodium selenate

Presentation

Continuous release intraruminal device. A cylindrical, blue glass continual release intraruminal device approximately 82mm x 24mm and weighing approximately 100g.

Use Medicines Responsibly. www.noah.co.uk

Are they different from other boluses?

Yes. Bimeda revolutionary boluses are completely unique

Through releasing sacrificial copper in the rumen, Cosecure is the only bolus designed to prevent and treat Thiomolybdate Toxicity before it occurs. As Thiomolybdate (MoS4) will first deplete copper in the rumen and, if there is not adequate copper there, bind to copper in the blood stream, it is vital that the bolus copper becomes active in the rumen. This is where Cosecure boluses are active. stomach

Some capsules deliver copper in the form of copper oxide. However copper oxide requires a low pH to become active. As the normal range of rumen pH is higher, between pH 5.5 and 6.5, it is chemically impossible for copper oxide to become active here. Copper oxide only becomes active in the abomasum (which has a pH range of 2 to 4), where it may simply be absorbed into the body and cannot stop the thiomolybdate uptake into the blood.

Cosecure is the only true dissolving bolus, and dissolves at a slow but constant rate.

Cattle Bolus Applicator Instructions

Cattle Applicator Instructions

Download Applicator Instructions

Monday, 13 August 2018 12:49

COSEICURE Sheep

Direct-to-Rumen, Continuous Release Nutritional Bolus pdfDownload the Data Sheet

USES

Supplies ionic copper, ionic cobalt, selenium and iodine at levels compatible with the animal’s daily requirements for up to eight months.

Each Bolus Contains:

  • 13.4% w/w ionic copper
  • 0.50% w/w ionic cobalt
  • 1.00% w/w iodine
  • 0.15% w/w selenium

Presentation

A cylindrical blue glass continual release intraruminal device.

*COSEICURE boluses are not a registered medicine, such as require authorisation by the HPRA

  • Warning: Copper Toxicity In Sheep & Lambs

    There is increased risk of copper toxicity associated with housed sheep and certain sheep breeds.

    • Please seek professional advice before using Cosecure or CoseIcure boluses in sheep/lambs housed or to be housed when the product is still active.
    • Please seek professional advice before using Cosecure or CoseIcure boluses in continental breeds and Blue Faced Leicesters which are more prone to copper toxicity.

Are they different from other boluses?

Yes. Bimeda revolutionary boluses are completely unique

As Thiomolybdate (MoS4) will first deplete copper in the rumen and, if there is not adequate copper there, bind to copper in the blood stream, it is vital that the bolus copper becomes active in the rumen. This is where Coseicure boluses are active. stomach sheep

Some capsules deliver copper in the form of copper oxide. However copper oxide requires a low pH to become active. As the normal range of rumen pH is higher, between pH 5.5 and 6.5, it is chemically impossible for copper oxide to become active here. Copper oxide only becomes active in the abomasum (which has a pH range of 2 to 4), where it may simply be absorbed into the body and cannot stop the thiomolybdate uptake into the blood.

Sheep Bolus Applicator Instructions

Sheep Applicator Instructions

Download Applicator Instructions

Page 7 of 8

The Story of Our Revolutionary Boluses

cosecure bolus

Would you believe our unique boluses came about through a unique partnership between Pilkington Glass and Animal Nutrition experts at the University of Leeds? To find out more about our extraordinary history, click here

BOLUSES AVAILABLE

cosecure

Available for cattle, sheep and lambs

  • check1IONIC COBALT
  • check1SELENIUM
  • check1IONIC COPPER

coseicure

Available for cattle and sheep

  • check1IONIC COBALT
  • check1SELENIUM
  • check1IONIC COPPER
  • check1IODINE

zincoisel

Available for sheep

  • check1IONIC ZINC
  • check1SELENIUM
  • check1IONIC COBALT
  • check1IODINE